Paper published: On network derivation, classification, and visualization: a response to Habeck and Moeller

For the second issue of Brain Connectivity, a new journal, we were invited to provide a response to a “controversial article” about issues of analysis and interpretation in fMRI.  In a fun paper, Elena, Eswar, Vince, and I provide our perspective and some better practices to continue the dialogue.

On network derivation, classification, and visualization: a response to Habeck and Moeller
Erik B. Erhardt, Elena A. Allen, Eswar Damaraju, Vince D. Calhoun.
Brain Connectivity 1(2), 2011.

Abstract
In the decade and a half since Biswal’s fortuitous discovery of spontaneous correlations in functional imaging data, the field of functional connectivity (FC) has seen exponential growth resulting in the identification of widely-replicated intrinsic networks and the innovation of novel analytic methods with the promise of diagnostic application.  As such a young field undergoing rapid change, we have yet to converge upon a desired and needed set of standards.  In this issue, Habeck and Moeller begin a dialogue for developing best practices by providing four criticisms with respect to FC estimation methods, interpretation of FC networks, assessment of FC network features in classifying sub-populations, and network visualization.  Here, we respond to Habeck and Moeller and provide our own perspective on the concerns raised in the hope that the neuroimaging field will benefit from this discussion.

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